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    Die Hector Fellow Academy stößt innovative Forschungsprojekte in neuen wissenschaftlichen Fragestellungen an.

Applications of Non-Invasive Ocular Signal Measurements

Margaret Clouse – Hector Fellow Eberhart Zrenner

Accommodation experiment set-up

An inevitable effect of the aging process is the development of presbyopia*, by which the eye is no longer able to adequately accommodate. As can be imagined, this phenomenon poses many challenges for the elderly portion of the population, making it difficult to perform tasks such as reading. At the time of this writing, no solution has been found that completely solves this problem.

Part of the difficulty inherent in finding a solution to this problem is the difficulty in measuring the key muscle involved in the process of accommodation. Traditionally, this has been a stumbling block for many researchers, as no reliable way of measuring the activity of this muscle existed. Groups studying accommodation have generally relied on imaging techniques to measure the movement of the ciliary muscle and associated bodies. While these methods have certainly added to our knowledge of accommodation, the underlying causes are still a mystery; in other words, we are observing the effects (muscle movement) without a clear understanding of the cause (electrical activity).

A goal of this PhD project supervised by Hector Fellow Eberhart Zrenner is to determine whether ciliary muscle activity could be reliably measured in a non-invasive manner (see Figure), with the end goal of developing a solution that could be used to correct presbyopia. Such a device would improve the quality of life for those suffering from presbyopia.

*) In German Altersweitsichtigkeit